Study of Factors Influencing the Intestinal Microbiota in Children from 0 to 3 Months at the Mother and Child Hospital of Bingerville, Ivory Coast during 2023
Grace Kemsol Miedjim *
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire and UFR Medical Science, University Félix Houphouet Boigny, Côte d’Ivoire.
Gbonon Mbengue Valérie
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Akaffou Adja Evelyne
Hôpital Mère et Enfant de Bingerville, Côte d'Ivoire.
Ndôh Ngrabé Nodje- Assal
CHU « la Renaissance » of Chad, Chad.
Ndri Kouamé Mathias
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Guede Cataud Marius
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Assohoun Egomli Stanislas
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire and University Jean Lorougnon Guédé, Côte d'Ivoire.
Marcelle Money Ettien
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Franck Djéda Gnahoré
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire and UFR Biosciences, University Félix Houphouet Boigny, Côte d'Ivoire.
Ambroise Kouamé Kintossou
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Kouamé Clarisse
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Kangah Tatiana
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Afran Sidjè Arlette
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire and UFR Biosciences, University Félix Houphouet Boigny, Côte d'Ivoire.
Diplo Flore
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Setchi Luc Olivier
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Koffi Stéphane
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
Dosso Mireille
Institut Pasteur de Côte d’Ivoire, Côte d’Ivoire.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Every human being builds a symbiosis with a diverse ecosystem of microorganisms: the intestinal microbiota. Its establishment, maturity, and composition evolving throughout life are dynamic processes influenced during their establishment by various factors such as gestational age, birth and feeding modalities, environment, and antibiotic use. The aim of this article is to identify the epidemiological characteristics (factors influencing the establishment and development of the intestinal microbiota) of populations of children from 0 to 3 months studied at the Mother and Child Hospital of Bingerville.
Methods: A longitudinal and prospective birth cohort of populations of children from Day 0 to Month 3 was conducted. Epidemiological data were collected from the mother after signing the informed consent form. Data collection tools included the survey form, information sheet, and informed consent form. Statistical analyses were performed using XLSTAT software version 2018. Chi-square test (significance test) was used on variables such as sex and gestational age, mode of delivery, gestational age and birth mode, and birth weight.
Results: A total of 52 infants were included. The socio-demographic and clinical characteristics of these newborns and their mothers were examined. Analysis of birth weight distribution according to mode of delivery and feeding mode did not reveal any significant association. Each studied characteristic was then discussed.
Conclusion: The objective of the study has been achieved. However, further research is needed to obtain more generalizable results.
Keywords: Factors influencing, intestinal microbiota, infants 0-3 months, Mother and Child Hospital