Lipid Based Drug Delivery System: A Review
Abdul-Hamid Abubakar Zubair *
Department of Biochemistry, Federal University Gashua, P.M.B 1005 Gashua, Yobe State, Nigeria.
Sadeeq Muhammad Sheshe
Department of Biochemistry, Kano State University of Science and Technology, P.M.B 3244, wudil, Kano State, Nigeria.
Muhammad Ribado Bashir
Department of Biological Sciences, Federal University Gusau, P.M.B 1001, Gusau, Zamfara State, Nigeria.
Sani Muhammad Sade
Department of Biochemistry, Federal University Lokoja, P.M.B 1154, Lokoja, Kogi State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Associated with the old/traditional of method of drug delivery are several limitation ranging from first-pass effect, low tolerance, minimal bioavailability, fluctuation of plasma drug concentration which result to less or no desired effect produced. This call for the demand for a more efficient drug administration technique. Lipid systems are biocompatible, inert and biodegradable, stable and deliver at the target with the desired effect. This paper attempt to describe several types of lipid particles used to deliver drug compounds and their applications as therapeutic agent in treating different clinical condition.
Keywords: Drug, biocompatible, biodegradable, bioavailability, lipids