Journal of Applied Life Sciences International https://journaljalsi.com/index.php/JALSI <p style="text-align: justify;"><strong>Journal of Applied Life Sciences International (ISSN:&nbsp;2394-1103)</strong> aims to publish high quality papers (<a href="/index.php/JALSI/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of ‘applied life sciences’. By not excluding papers on the basis of novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> SCIENCEDOMAIN international en-US Journal of Applied Life Sciences International 2394-1103 Assessment of Some Heavy Metals and Physico-Chemical Parameters of Surface Water of Matara-Uku Wetlands https://journaljalsi.com/index.php/JALSI/article/view/30193 <p>The study assessed the levels of Nitrogen, Phosphorous and some heavy metals in Matara-Uku wetland. Twenty water samples were collected from surface water of Matara-Uku using polyethene plastic container, the physicochemical parameters of the samples were measured and the samples were analyzed for Nitrogen, Phosphorous and heavy metals. Results from physicochemical analysis are obtained as; pH (7.6 – 8.0), total dissolve solid (70.82 - 84.26 mg/l), electric conductivity (105.0 – 163.0 μs/cm) and temperature (24.4 – 25.4ºC). All the results are in line with World Health Organization standard of 6.5 - 8.5, &lt;600 mg/l, 400 μs/cm and ambient temperature respectively. &nbsp;The Nitrogen and phosphorous were analyzed using UV- Visible spectrophotometer. From the results, it was found that all the samples had Nitrogen level below the World Health Organization maximum contaminant level of 10 mg/L with a mean concentration range (0.2293 ± 0.0057) mg/L to (2.2455 ± 0.0216) mg/L. Phosphorus was also analyzed and the results indicated that all the sampling sites had phosphorus level above the WHO maximum contaminant level of 0.03 mg/L with a mean concentration range (3.8208 ± 0.4109) mg/L to (4.56 ± 0.1325) mg/L. The water samples were digested using concentrated HCl and HNO<sub>3, </sub>in which the digested samples were used for heavy metals analysis using Atomic Absorption Spectrophotometer (AAS). The mean concentrations of the heavy metals analyzed were between the ranges Pb (0.1272 ± 0.0445) mg/L to (0.2727 ± 0.1285) mg/L, Cd (0.0026 ± 0.0024) mg/L to (0.0053 ± 0.0054) mg/L and Ni (0.0705 ± 0.0235) mg/L to (0.1411 ± 0.0819) mg/L respectively. Concentrations of Cd and Ni are generally below the maximum permissible limit of 0.03 mg/L and 0.02 mg/L, whereas concentrations of Pb exceeded the maximum permissible limit of 0.01 mg/L for surface water. It was concluded that the surface water of Matara-Uku is polluted with respect to Pb, which is known to bio-accumulate and even undergo bio-magnification in organisms such as fishes and even plants with serious health implications to human being.</p> Abbas Umar Haruna Yahaya Abdullahi Muhammad Zaharaddeen Muhammad Misbahu Said Ahmad Fatima Abdullahi Goje Musbahu Ibrahim ##submission.copyrightStatement## 2020-11-21 2020-11-21 1 12 10.9734/jalsi/2020/v23i1130193 Bacterial Multidrug Resistant Patterns Associated with Intensive Care Unit Infections in Akum, Cameroon https://journaljalsi.com/index.php/JALSI/article/view/30194 <p><strong>Background: </strong>Patients admitted into the intensive care unit (ICU) usually have impaired immunity and are therefore at high risk of acquiring hospital associated infections. Infections caused by multidrug resistant bacteria now constitute a major problem, limiting the choice of antimicrobial therapy.</p> <p><strong>Objectives: </strong>This study was aimed at determining the antimicrobial resistance pattern of pathogens causing ICU infections at the Catholic Holy Family Hospital Akum-Bamenda. The etiological agents, prevalence and types ICU infections were also determined.</p> <p><strong>Methods:</strong> Thirteen months hospital associated infections surveillance was conducted in the hospital for patients admitted into ICU. Blood, urine, tracheal aspirate and wound biopsies specimens were collected under strict asepsis and sent to the Medical Microbiology laboratory of the same institution for immediate processing. All pathogens were isolated and identified by standard microbiological methods. Disk diffusion antibiotic susceptibility testing was performed and interpreted according to Clinical and Laboratory Standards Institute (CLSI) guidelines.</p> <p><strong>Results:</strong> The overall prevalence of ICU infections was 30.9% out of which 12.9% were bloodstream infections, 31.5% urinary tract infections, 38.9% pneumonia, and 16.7% skin and soft tissue infections. <em>Klebsiella</em> species and <em>Escherichia coli</em> were the predominant pathogens. Multidrug resistant organisms constituted 59.3% of the pathogens, MDR <em>Klebsiella</em> spp and MDR <em>E. coli</em> were 70.8% and 71.4% respectively. Resistance to Cefuroxime was the highest (92.9%) while Meropenem had the least resistance (21.4%).</p> <p><strong>Conclusion:</strong> There is a high prevalence of multidrug resistant bacteria causing ICU infections.&nbsp; With the advent of covid-19, infection control procedures and institution of functional antimicrobial stewardship are needed to be put in place in order to cover come this herculean task.</p> Asakizi Augustine Nji Forcham Emmanuel Duna ##submission.copyrightStatement## 2020-11-27 2020-11-27 13 21 10.9734/jalsi/2020/v23i1130194